Dr. Alok Srivastava - Scientific Publications

Scientific publications

• Sabapathy V, Ravi S, Srivastava V, Srivastava A, Kumar S. Long-term cultured human term placenta-derived mesenchymal stem cells of maternal origin displays plasticity. Stem Cells Int. 2012:174328. Epub 2012 Mar 26.
• Varatharajan S, Abraham A, Zhang W, Shaji RV, Ahmed R, Abraham A, George B, Srivastava A, Chandy M, Mathews V, Balasubramanian P. Carbonyl reductase 1expression influences daunorubicin metabolism in acute myeloid leukemia. Eur J Clin Pharmacol. 2012 May 5.
• David S, Jayandharan GR, Abraham A, Jacob RR, Devi GS, Patkar N, Shaji RV, Nair SC, Viswabandya A, Ahmed R, George B, Mathews V, Chandy M, Srivastava A. Molecular basis of Wiskott-Aldrich syndrome in patients from India. Eur J Haematol. 2012 Jun 9. doi: 10.1111/j.1600-0609.2012.01818.x.
• Rajkumar AP, Poonkuzhali B, Kuruvilla A, Srivastava A, Jacob M, Jacob KS. Outcome definitions and clinical predictors influence pharmacogenetic associations between HTR3A gene polymorphisms and response to clozapine in patients with schizophrenia. Psychopharmacology (Berl). 2012 Jun 15.
• Edison ES, Sathya M, Rajkumar SV, Nair SC, Srivastava A, Shaji RV. A novel β-globin gene mutation HBB.c.22 G>C produces a hemoglobin variant (Hb Vellore) mimicking HbS in HPLC. Int J Lab Hematol. 2012 Apr 4. doi:10.1111/j.1751-553X.2012.01418.x
• Peter CV, Chakrapani A, Shah S, Shah A, Srivastava A. Blastic plasmacytoid dendritic cell neoplasm presenting as fever with diffuse cutaneous nodules. Indian J Dermatol. 2012 Jan;57(1):45-7.
• Patkar N, Alex AA, B B, Ahmed R, Abraham A, George B, Vishwabandya A, Srivastava A, Mathews V. Standardizing minimal residual disease by flow cytometryfor precursor B lineage acute lymphoblastic leukemia in a developing country. Cytometry B Clin Cytom. 2012 Jul;82(4):252-8.
• Sellathamby S, Lakshmi KM, Busson M, Viswabandya A, George B, Mathews V, Chandy M, Charron D, Krishnamoorthy R, Tamouza R, Srivastava A. Polymorphisms in the Immunoregulatory Genes are Associated with Hematopoietic Recovery and Increased Susceptibility to Bacterial Infections in Patients with Thalassaemia Major Undergoing Matched Related Hematopoietic Stem Cell Transplantation. Biol Blood Marrow Transplant. 2012 Jan 16. [Epub ahead of print]
• Chendamarai E, Balasubramanian P, George B, Viswabandya A, Abraham A, Ahmed R, Alex AA, Ganesan S, Lakshmi KM, Sitaram U, Nair SC, Chandy M, Janet NB, Srivastava VM, Srivastava A, Mathews V. Role of minimal residual disease monitoring in acute promyelocytic leukemia treated with arsenic trioxide in frontline therapy. Blood. 2012 Feb 28. [Epub ahead of print]
• Jayandharan GR, Srivastava A, Srivastava A. Role of molecular genetics in hemophilia: from diagnosis to therapy. Semin Thromb Hemost. 2012 Feb;38(1):64-78. Epub 2012 Feb 7.
• Abraham A, Varatharajan S, Abbas S, Zhang W, Shaji RV, Ahmed R, Abraham A, George B, Srivastava A, Chandy M, Mathews V, Balasubramanian P. Cytidine deaminase genetic variants influence RNA expression and cytarabine cytotoxicity in acute myeloid leukemia.  Pharmacogenomics. 2012 Feb;13(3):269-82.
• Balasubramanian P, Chendamarai E, Markose P, Fletcher L, Branford S, George B, Mathews V, Chandy M, Srivastava A. International Reporting Scale of BCR-ABL1 Fusion Transcript in Chronic Myeloid Leukemia: First Report from India. Acta Haematol. 2012;127(3):135-42. Epub 2012 Jan 12.
• Balasubramanian P, Desire S, Panetta JC, Lakshmi KM, Mathews V, George B, Viswabandya A, Chandy M, Krishnamoorthy R, Srivastava A. Population pharmacokinetics of cyclophosphamide in patients with thalassemia major undergoing HSCT. Bone Marrow Transplant. 2012 Jan 9. doi: 10.1038/bmt.2011.254. [Epub ahead of print]
• Viswabandya A, Baidya S, Nair SC, Abraham A, George B, Mathews V, Chandy M, Srivastava A. Correlating clinical manifestations with factor levels in rare bleeding disorders: a report from Southern India. Haemophilia. 2012 Jan 4. doi:10.1111/j.1365-2516.2011.02730.x. [Epub ahead of print]
• Mathews V, Chendamarai E, George B, Viswabandya A, Srivastava A. Treatment of acute promyelocytic leukemia with single-agent arsenic trioxide. Mediterr J Hematol Infect Dis. 2011;3(1):e2011056. Epub 2011 Nov 28.
• Nair SC, Viswabandya A, Srivastava A. Diagnosis and management of von Willebrand disease: a developing country perspective. Semin Thromb Hemost. 2011 Jul;37(5):587-94. Epub 2011 Nov 18.
• Sumitha E, Jayandharan GR, David S, Jacob RR, Sankari Devi G, Bargavi B, Shenbagapriya S, Nair SC, Abraham A, George B, Viswabandya A, Mathews V, Chandy M, Srivastava A. Molecular basis of Bernard-Soulier syndrome in 27 patients from India. J Thromb Haemost. 2011 Aug;9(8):1590-8
• Patkar N, Nair S, Alex AA, Parihar M, Manipadam MT, Arora N, Ahmed R, Abraham A, George B, Viswabandya A, Srivastava V, Srivastava A, Mathews V. Clinicopathological features of hepatosplenic T cell lymphoma: a single centre experience from India. Leuk Lymphoma. 2011 Dec 5. [Epub ahead of print]
• Edison ES, Shaji RV, Chandy M, Srivastava A. Interaction of Hemoglobin E with Other Abnormal Hemoglobins. Acta Haematol. 2011 Oct 4;126(4):246-248.
• Moorthy RK, Sam GA, Kumar SV, Chacko G, Mathews V, Chacko AG, Srivastava A, Rajshekhar V. Intralesional mesenchymal stromal cell transplant in a rodent model of cortical cryoinjury. Neurol India. 2011 Jul-Aug;59(4):573-8.
• Bugalia A, Abraham A, Balasubramanian P, Srivastava A, Nair S. Mast cell sarcoma of the small intestine: a case report. J Clin Pathol. 2011 Jul 21. [Epub ahead of print] PubMed PMID: 21778298.
• Parihar M, Ashok Kumar J, Sitaram U, Balasubramanian P, Abraham A, Viswabandya A, George B, Mathews V, Srivastava A, Srivastava VM. Cytogenetic analysis of acute myeloid leukemia with t(8;21) from a tertiary care center in India with correlation between clinicopathologic characteristics and molecular analysis. Leuk Lymphoma. 2011 Sep 2. [Epub ahead of print] PubMed PMID: 21745004.
• Manipadam MT, Nair S, Viswabandya A, Mathew L, Srivastava A, Chandy M. Non-Hodgkin lymphoma in childhood and adolescence: frequency and distribution of immunomorphological types from a tertiary care center in South India. World J Pediatr. 2011 Jun 1. [Epub ahead of print] PubMed PMID: 21633853.
• Gupta M, Ashok Kumar J, Sitaram U, Neeraj S, Nancy A, Balasubramanian P, Abraham A, Mathews V, Viswabandya A, George B, Chandy M, Srivastava A, Srivastava VM. The t(6;9)(p22;q34) in myeloid neoplasms: a retrospective study of 16 cases. Cancer Genet Cytogenet. 2010 Dec;203(2):297-302.
• Padankatti SM, Macaden AS, Cherian SM, Thirumugam M, Pazani D, Kalaiselvan M, John JA, Subbian E, Prakash H, Poonnoose PM, Kavitha ML, Devadarasini M, Viswabandya A, Mathews V, Srivastava A. A patient-prioritized ability assessment in haemophilia: the Canadian Occupational Performance Measure. Haemophilia. 2011; 17:605-11
• Stonebraker JS, Bolton-Maggs PH, Brooker M, Farrugia A, Srivastava A. A study of reported factor IX use around the world. Haemophilia. 2011 Feb 7. doi: 10.1111/j.1365-2516.2010.02461.
• Gupta M, Ashok Kumar J, Sitaram U, Neeraj S, Nancy A, Balasubramanian P, Abraham A, Mathews V, Viswabandya A, George B, Chandy M, Srivastava A, Srivastava VM. The t(6;9)(p22;q34) in myeloid neoplasms: a retrospective study of 16 cases. Cancer Genet Cytogenet. 2010 Dec;203(2):297-302.
• George B, Mathews V, Viswabandya A, Lakshmi KM, Srivastava A, Chandy M. Allogeneic hematopoietic stem cell transplantation is superior to immunosuppressive therapy in Indian children with aplastic anemia: a single-center analysis of 100 patients. Pediatr Hematol Oncol. 2010;27:122-31.
• Viswabandya A, Baidya S, Nair SC, Lakshmi KM, Mathews V, George B, Chandy M, Srivastava A. Clinical manifestations of combined factor V and VIII deficiency: a series of 37 cases from a single center in India. Am J Hematol. 2010;85(7):538-9.
• Preston FE, Lippi G, Favaloro EJ, Jayandharan GR, Edison ES, Srivastava A. Quality issues in laboratory haemostasis. Haemophilia. 2010 Jul;16 Suppl 5:93-9.
• Nair SC, Dargaud Y, Chitlur M, Srivastava A. Tests of global haemostasis and their applications in bleeding disorders. Haemophilia. 2010;16 Suppl 5:85-92.
• V. Mathews, B. George, E. Chendamarai, K M Lakshmi, S. Desire, P. Balasubramanian, A. Viswabandya, R. Thirugnanam, A. Abraham, R.V. Shaji, A. Srivastava, M. Chandy. Single agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: Long Term Follow Up Data. J Clin Oncol 2010; 28: 3866-71
• Rajasekar R, Lakshmi KM, George B, Viswabandya A, Thirugnanam R, Abraham A, Chandy M, Srivastava A, Mathews V. Dendritic cell count in the graft predicts relapse in patients with hematological malignancies undergoing a HLA-matched related allogeneic peripheral blood stem cell transplant. Biol Blood MarrowTransplant. 2010; 16: 854-60
• George B, Mathews V, Viswabandya A, Lakshmi KM, Srivastava A, Chandy M. Allogeneic hematopoietic stem cell transplantation is superior to immunosuppressive therapy in Indian children with aplastic anemia - A single-center analysis of 100 patients. Pediatr Hematol Oncol. 2010Mar;27(2):122-31.
• Stonebraker JS, Brooker M, Amand RE, Farrugia A, Srivastava A. A study of reported factor VIII use around the world. Haemophilia. 2010 Jan;16(1):33-46.
• Markose P, Chendamarai E, Balasubramanian P, Velayudhan SR, Srivastava VM, Mathews V, George B, Viswabandya A, Srivastava A, Chandy M. Spectrum of BCR-ABL kinase domain mutations in patients with chronic myeloid leukemia from India with suspected resistance to imatinib-mutations are rare and have different distributions. Leuk Lymphoma. 2009 Dec;50(12):2092-5.
• Mathews V, Nair SC, David S, Viswabandya A, Srivastava A. Management of hemophilia in patients with inhibitors: the perspective from developing countries. Semin Thromb Hemost. 2009 Nov;35(8):820-6.
• Thirugnanam R, George B, Chendamarai E, Lakshmi KM, Balasubramanian P, Viswabandya A, Srivastava A, Chandy M, Mathews V. Comparison of clinical outcomes of patients with relapsed acute promyelocytic leukemia induced with arsenic trioxide and consolidated with either an autologous stem cell transplant or an arsenic trioxide-based regimen. Biol Blood Marrow Transplant. 2009 Nov;15(11):1479-84.
• Desire S, Balasubramanian P, Bajel A, George B, Viswabandya A, Mathews V, Srivastava A, Chandy M. Frequency of TPMT alleles in Indian patients with acute lymphatic leukemia and effect on the dose of 6-mercaptopurine. Med Oncol. 2009 Oct 15. [Epub ahead of print]
• Srivastava A. Indian Academy of Neurology: The Dasgupta Oration 2009, Neural regeneration with stem cells: Rebooting the brain. Ann Indian Acad Neurol. 2009 Jul;12(3):138-9.
• Pavlova A, Brondke H, Müsebeck J, Pollmann H, Srivastava A, Oldenburg J. Molecular mechanisms underlying hemophilia A phenotype in seven females. J Thromb Haemost. 2009 Jun;7(6):976-82.
• Jayandharan GR, Nair SC, Poonnoose PM, Thomas R, John J, Kesha SK, Cherian RS, Devadarshini M, Lakshmi MK, Shaji RV, Viswabandya A, George B, Mathews V, Chandy M, Srivastava A. Pomymorphisms in the FVII gene modified phenotypic heterogeneity of severe haemophilia.  Haemophilia 2009; 15: 1228-36
• George B, Mathews V, Viswabandya A, Srivastava A, Chandy M. Fludarabine based reduced intensity conditioning for regimens for allowgeneic stem cell transplantation in patients with aplastic anemia and fungal infections. Clin Transplant. 2009; 23: 228-32
• Rajashekar R, Mathews V, Lakshmi ML, George B, Viswabandya A, Chandy M, Srivastava A. Cellular immune reconstitution and its impact on clinical outcome in children with beta thalassemia major undergoing a matched related myeloablative allogeneic bone marrow transplantation. Biol Blood Marrow Transplant. 2009; 15:597-609
• Mathews V, George B, Lakshmi KM, Viswabandya A, John JM, Sitaram U, Daniel D, Chandy M, Srivastava A. Impact of pretransplant splenectomy on patients with beta-thalassemia major undergoing a matched-related allogeneic stem cell transplantation. Pediatr Transplant. 2009;13:171-6
• I. Hyun, Lindvall O, …, Srivastava A, …, Daley GQ. New ISSCR Guidelines underscores major principles for responsible translational stem cell research. Cell Stem Cell 2008; 3: 607-9.
• Bajel A, George B, Mathews V, Viswabandya A, Srivastava A, Chandy M. Treatment of children with acute lymphoblastic leukemia in India using a BFM protocol. Pediatr Blood Cancer. 2008 Nov;51(5):621-5. .
• Rodeghiero F, Ruiz-Sáez A, Bolton-Maggs PH, Hayward CP, Nair SC, Srivastava A. Laboratory issues in bleeding disorders. Haemophilia. 2008 Jul;14 Suppl 3:93-103.
• Srivastava A, Hoots K, Soucie JM, Ludlam CA. Linking the world with training and research for improving haemophilia care. Haemophilia. 2008 ; 14 (Suppl 3): 43-8.
• Ponder KP, Srivastava A. Walk a mile in the moccasins of people with haemophilia. Haemophilia. 2008 May;14(3):618-20.
• Vassord C, Lapouméroulie C, Koumaravelou K, Srivastava A, Krishnamoorthy R. Endothelial cells do not express GSTA1: potential relevance to busulfan-mediated endothelial damage during haematopoietic stem cell transplantation. Eur J Haematol. 2008 Apr;80(4):299-302.
• Viswabandya A, Mathews V, George B, Nair SC, Baidya S, Mammen JJ, Chandy M, Srivastava A. Successful surgical haemostasis in patients with von Willebrand disease with Koate (R) DVI. Haemophilia. 2008; 14(4): 763-7
• Jayandharan GR, Srivastava A. The phenotypic heterogeneity of severe hemophilia. Semin Thromb Hemost. 2008 Feb;34(1):128-41
• Edison ES, Shaji RV, Devi SG, Moses A, Viswabandya A, Mathews V, George B, Srivastava A, Chandy M. Analysis of beta globin mutations in the Indian population: presence of rare and novel mutations and region-wise heterogeneity. Clin Genet. 2008 Apr;73(4):331-7
• Rajasekar R, Mathews V, Lakshmi KM, Sellathamy S, George B, Viswabandya A, Daniel D, Chandy M, Srivastava A. Plasmacytoid dendritic cell count on day 28 in HLA-matched related allogeneic peripheral blood stem cell transplant predicts the incidence of acute and chronic GVHD. Biol Blood Marrow Transplant. 2008 Mar;14(3):344-50
• George B, Mathews V, Viswabandya A, Kavitha ML, Srivastava A, Chandy M. Fludarabine based reduced intensity conditioning regimens in children undergoing allogeneic stem cell transplantation for severe aplastic anemia. Pediatr Transplant. 2008 Feb;12(1):14-9.
• Poonnoose PM, Thomas R, Keshava SN, Cherian RS, Padankatti S, Pazani D, Kavitha ML, Devadarsini M, Bhattacharjee S, Viswabandya A, John JA, Macaden AS, Mathews V, Srivastava A. Psychometric analysis of the Functional Independence Score in Haemophilia (FISH). Haemophilia 2007; 13:620-6.
• Feldman BM, Aledort L, Bullinger M, Delaney FM, Doria AS, Funk S, Giangrande P, Lundin B, Manco-Johnson M, Miners A, Scriba PC, Srivastava A, Schramm W, Blanchette VS; Second International Prophylaxis Study Group. The economics of haemophilia prophylaxis: governmental and insurer perspectives. Proceedings of the Second International Prophylaxis Study Group (IPSG) symposium. Haemophilia. 2007 Nov;13(6):745-9.
• Mathews V, George B, Deotare U, Lakshmi KM, Viswabandya A, Daniel D, Chandy M, Srivastava A. A new stratification strategy that identifies a subset of class III patients with an adverse prognosis among children with beta thalassemia major undergoing a matched related allogeneic stem cell transplantation. Biol Blood Marrow Transplant. 2007 Aug;13(8):889-94.
• Jayandharan G, Spreafico M, Viswabnadya A, Chandy M, Srivastava A, Peyvandi F. Mutations in the MCFD2 gene are predominant among patients with hereditary combined FV and FVIII deficiency (F5F8D) in India. Haemophilia 2007 Jul; 13(4): 413-9.
• Lee VN, Srivastava A, Nithyananth M, Kumar P, Cherian VM, Viswabandya A, Mathews V, George B, Vnekatesh K, Nair SC, Chandy M, Sunderaraj GD.  Fracture neck of femur – experience from a cohort of 11 patients from a tertiary center in India. Haemophilia 2007 Jul; 13(4):391-4.
• Jayandharan G, Viswabandya A, Nair SC, Chandy M, Srivastava A. Molecular basis of hereditary factor VII deficiency in India: five novel mutations including a double missense mutation (Ala191Glu; Trp364Cys) in 11 unrelated patients. Haematologica 2007 Jul; 92(7): 1002-3.
• Mathews V, Thomas M, Srivastava VM, George B, Srivastava A, Chandy M. Impact of FLT3 mutations and secondary cytogenetic changes on the outcome of patients with newly diagnosed acute promyelocytic leukemia treated with single agent arsenic trioxide regimen. Haematologica 2007 Jul; 92(7):994-5
• Bajel A, George B, Mathews V, Viswabandya A, Kavitha ML, Srivastava A, Chandy M. Adult ALL: Treatment outcome and prognostic factors in an Indian population using a modified German ALL (GMALL) protocol. Leukemia 2007 Jun 7.
• George B, Mathews V, Viswabandya A, Kavitha ML, Srivastava A, Chandy M. Fludarabine and cyclophosphamide based reduced intensity conditioning (RIC) regimens reduce rejection and improve outcome in Indian patients undergoing allogeneic stem cell transplantation for severe aplastic anemia. Bone Marrow Transplant. 2007 Jul;40(1):13-8
• Mammen J, Nair SC, Srivastava A. Extrenal quality assessment scheme for hemostasis in India. Semin Thromb Hemost 2007; 33(3):265-72
• Manipadam MT, Viswabandya A, Srivastava A. Primary splenic marginal zone lymphoma with florid granulomatous reaction--a case report and review of literature. Pathol Res Pract. 2007;203(4):239-43.
• Jayandharan G, Nelson EJ, Baidya S, Chandy M, Srivastava A. A new multiplex PCR and conformation sensitive gel electrophoresis strategy for mutation detection in the platelet glycoprotein alpha beta genes. J Thromb Haemost. 2006 Oct 31
• Nelson EJ, Nair SC, Peretz H, Coller BS, Seligsohn U, Chandy M, Srivastava A. Diversity of Glanzmann thrombasthenia in southern India: 10 novel mutations identified among 15 unrelated patients. J Thromb Haemost. 2006 Aug;4(8):1730-7
• Beeton K, De Kleijn P, Hilliard P, Funk S, Zourikian N, Bergstrom BM, Engelbert RH, Van Der Net JJ, Manco-Johnson MJ, Petrini P, Van den Berg M, Abad A, Feldman BM, Doria AS, Lundin B, Poonnoose PM, John JA, Kavitha ML, Padankatti SM, Devadarasini M, Pazani D, Srivastava A, Van Genderen FR, Vachalathiti R. Recent developments in clinimetric instruments. Haemophilia. 2006 Jul;12 Suppl 3:102-7
• Peyvandi F, Jayandharan G, Chandy M, Srivastava A, Nakaya SM, Johnson MJ, Thompson AR, Goodeve A, Garagiola I, Lavoretano S, Menegatti M, Palla R, Spreafico M, Tagliabue L, Asselta R, Duga S, Mannucci PM. Genetic diagnosis of haemophilia and other inherited bleeding disorders. Haemophilia. 2006 Jul;12 Suppl 3:82-9.
• Lillicrap D, Nair SC, Srivastava A, Rodeghiero F, Pabinger I, Federici AB. Laboratory issues in bleeding disorders. Haemophilia. 2006 Jul;12 Suppl 3:68-75.
• Hertzberg MS, Mammen J, McCraw A, Nair SC, Srivastava A. Achieving and maintaining quality in the laboratory. Haemophilia. 2006 Jul;12 Suppl 3:61-7.
• Mathews V, George B, Lakshmi K M, Viswabandya A, Bajel A, Balasubramanian P, Shaji R V, Srivastava A, Chandy M. Single-agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: durable remissions with minimal toxicity. Blood 2006; 107: 2627-32.
• Jayandharan G R, Viswabandya A, Baidya S, Nair SC, George B, Mathews V, Chandy M, Srivastava A. Mutations in coagulation factor XIII A gene in eight unrelated Indians. Five novel mutations identified by a novel PCR-CSGE approach. Thromb Haemost 2006; 95: 551-6
• Sellathamby S, Balasubramanian P, Sivalingam S, Shaji R V, Mathews V, George B, Viswabandya A, Srivastava A, Chandy M. Developing an algorithm of informative markers for evaluation of chimerism after allogeneic bone marrow transplantation. Bone Marrow Transplant 2006; 37: 751-5
• Castaman G, Rodeghiero F, Tosetto A, Cappelletti A, Baudo F, Eikenboom JC, Federici AB, Lethagen S, Linari S, Lusher J, Nishino M, Petrini P, Srivastava A, Ungerstedt JS. Hemorrhagic symptoms and bleeding risk in obligatory carriers of type 3 von Willebrand disease: an international, multicenter study. J Thromb Haemost. 2006 Oct;4(10):2164-9.
• Sadler JE, Budde U, Eikenboom JC, Favaloro EJ, Hill FG, Holmberg L, Ingerslev J, Lee CA, Lillicrap D, Mannucci PM, Mazurier C, Meyer D, Nichols WL, Nishino M, Peake IR, Rodeghiero F, Schneppenheim R, Ruggeri ZM, Srivastava A, Montgomery RR, Federici AB; Working Party on von Willebrand Disease Classification. Update on the pathophysiology and classification of von Willebrand disease: a report of the Subcommittee on von Willebrand Factor. J Thromb Haemost. 2006 Oct;4(10):2103-14.
• George B, Mathews V, Viswabandya A, Srivastava A, Chandy M. Infections in children undergoing allogeneic bone marrow transplant. Pediatr Transplant. 2006; 10:48-54.
• Rodeghiero F, Castaman G, Tosetto A, Batlle J, Baudo F, Cappelletti A, Casana P, De Bosch N, Eikenboom JC, Federici AB, Lethagen S, Linari S, Srivastava A.The discriminant power of bleeding history for the diagnosis of type 1 von Willebrand disease: an international, multicenter study. J Thromb Haemost. 2005:3:2619-26.
• Srivastava A. Uncertain times for research on hemophilia and allied disorders. J Thromb Haemost 2006; 4: 680
• Poonnoose PM, Srivastava A. Functional assessment of arthropathy – An international perspective. Semin Hematol 2006; 43 (Suppl 1): 27-32
• Srivastava A, Rodeghiero F. Epidemiology of von Willebrand disease in developing countries. Semin Thromb Hemost. 2005;31(5):569-76.
• Mathews V, Viswabandya A, Baidya S, George B, Nair S, Chandy M, Srivastava A.  Surgery for hemophilia in developing countries. Semin Thromb Hemost. 2005;31(5):538-43.
• Srivastava A, You SK, Ayob Y, Chuansumrit A, de Bosch N, Perez Bianco R, Ala F. Hemophilia treatment in developing countries: products and protocols. Semin Thromb Hemost. 2005;31(5):495-500.
• G. Jayandharan, R.V. Shaji, S.C. Nair, M. Chandy and A. Srivastava. Novel missense mutations in two patients with factor XI deficiency (Val271Leu and Tyr351Ser) and one patient with combined factor XI and factor IX deficiency       (Phe349Val). Thromb Haemost 2005;94: 808-811.
• Jayandharan GJ, Shaji RV, Baidya S, Nair SC, Chandy M, Srivastava A. Molecular characterization of factor IX gene mutations in 53 patients with haemophilia B in India.  Thromb Haemost 2005;94:883-886.
• Poonnoose PM, Manigandan C, Thomas R, Shyamkumar NK, Kavitha ML, Bhattacharji S, Srivastava A. Functional Independence Score in Haemophilia: a new performance-based instrument to measure disability. Haemophilia. 2005;11(6):598-602.
• Poonkuzhali B, Shaji RV, Salamun DE, George B, Srivastava A, Chandy M. Cytochrome P4501A1 and glutathione S transferase gene polymorphisms in patients with aplastic anemia in India. Acta Haematol. 2005;114(3):127-32.
• Srivastava A. Optimizing clotting factor replacement therapy in hemophilia: A global need. Hematology. 2005;10 Suppl 1:229-30.
• Chandy M, Balasubramanian P, Shaji R V, Mathews V, George B, Dennison D, Krishnamoorthy R, Srivastava A. Randomized trial of two different conditioning regimes for BMT in thalassaemia – The role of busulfan pharmacokinetics in determining outcome. Bone Marrow Transplant. 2005;36(10):839-45.
• Jayandharan G, Shaji RV, Baidya S, Nair SC, Chandy M, Srivastava A. Identification of factor VIII gene mutations in 101 patients with haemophilia A: mutation analysis by inversion screening and multiplex PCR and CSGE and molecular modelling of 10 novel missense substitutions. Haemophilia. 2005; 11(5):481-91.
• Edison ES, Shaji RV, Srivastava A, Chandy M. Compound heterozygosity for Hb E and Hb Lepore-Hollandia in India; first report and potential diagnostic pitfalls. Hemoglobin. 2005;29(3):221-4.
• Edison ES, Shaji RV, Srivastava A, Chandy M. Hyperbilirubinemia in homozygous HbE disease is associated with the UGT1A1 gene polymorphism. Hemoglobin. 2005; 29(3): 189-95.
• Damodar S, George B, Mammen J, Mathews V, Srivastava A, Chandy M. Pre-transplant reduction of isohaemagglutinin titres by donor group plasma infusion does not reduce the incidence of pure red cell aplasia in major ABO-mismatched transplants. Bone Marrow Transplant. 2005 Aug;36(3):233-5.
• Srivastava A. Gene therapy for hemophilia.  J Thromb Haemost 2005; 3:1313
• Jayandharan G, Viswabandya A, Baidya S, Nair SC, Shaji RV, George B, Chandy M, Srivastava A. Six novel mutations including triple heterozygosity for Phe31Ser, 514delT and 516T-->G factor X gene mutations are responsible for congenital factor X deficiency in patients of Nepali and Indian origin. J Thromb  Haemost 2005; 3(7):1482-7.
• Jayandharan G, Viswabandya A, Baidya S, Nair SC, Shaji RV, Chandy M, Srivastava A. Molecular genetics of hereditary prothrombin deficiency in Indian patients: identification of a novel Ala362 --> Thr (Prothrombin Vellore 1) mutation. J Thromb Haemost 2005; 3(7): 1446-53.
• F. Rodeghiero, G. Castaman, A. Tosetto, J. Batlle, F.Baudo, A. Cappelletti, P. Casana, S.N. De Bosch, J C J Eikenboom, A.B. Federici, S. Lethagen, S.Linariss and A. Srivastava.  The discriminant power of bleeding history for the diagnosis of type 1 von Willebrand disease: an international, multicenter study. J Thromb Haemost. 2005; 3: 2619-2626.
• E.J.R. Nelson, J.LI, W.B. Mitchell, M. Chandy, A.Srivastava and B.S. Coller. Three novel b-propeller mutations causing Glanzmann thrombasthenia result in production of normally stable pro-aIIb,but variably impaired progression of pro-aIIbb3 from endoplasmic reticulum to Golgi. J Thromb Haemost. 2005; Jul; 3(7): 2773-2783.
• Edison ES, Shaji RV, Devi SG, Kumar SS, Srivastava A, Chandy M. Hb Showa-Yakushiji [beta110(G12)Leu-->Pro] in four unrelated patients from west Bengal. Hemoglobin. 2005;29(1):19-25.
• Srivastava A. von Willebrand disease in the developing world. Semin Hematol. 2005; 42(1):36-41
• George B, Mathews V, Shaji RV, Srivastava V, Srivastava A, Chandy M. Fludarabine-based conditioning for allogeneic stem cell transplantation for multiply transfused patients with Fanconi's anemia. Bone Marrow Transplant. 2005; 35(4):341-3.
• George B, Poonkuzhali B, Srivastava VM, Chandy M, Srivastava A. Hematological and molecular remission with combination chemotherapy in a patient with PLZF-RARalpha acute promyelocytic leukemia (APML). Ann Hematol. 2005;84(6):406-8.
• Srivastava A, Poonkuzhali B, Shaji RV, George B, Mathews V, Chandy M, Krishnamoorthy R. Glutathione S-Transferase M1 Polymorphism- A Risk Factor For HepaticVeno-occlusive Disease In Bone Marrow Transplantation. Blood. 2004;104:1574-1577.
• Srivastava A. Dose and response in haemophilia: Optimization of factor replacement therapy. Br J Haematol 2004;127:12-25.
• Jayandharan G, Shaji RV, George B, Chandy M, Srivasatva A. Informativeness of linkage analysis for genetic diagnosis of haemophilia A in India. Haemophilia 2004; 10:553-9.
• Fischer K, Van Den Berg HM, Thomas R, Kumar S, Poonnoose P, Viswabandya A, Mathews V, Kavitha ML, Bhattacharjee S, Srivastava A. Dose and outcome of care in haemophilia – how do we define cost-effectiveness? Haemophilia 2004; 10(suppl4): 216-20.
• Evatt BL, Black C, Batorova A, Street A, Srivastava A. Comprehensive care for haemophilia around the world. Haemophilia. 2004 Oct;10 Suppl 4:9-13.
• George B, Mathews V, Poonkuzhali B, Shaji RV, Srivastava A, Chandy M. Treatment of children with newly diagnosed acute promyelocytic leukemia with arsenic trioxide: a single center experience. Leukemia 2004; 18:1587-90.
• George B, Mathews V, Srivastava A, Chandy M. Infections among allogeneic bone marrow transplant recipients in India. Bone Marrow Transplant. 2004;33(3):311-5
• Lee V, Srivastava A, Palani Kumar C, Daniel AJ, Mathews V, Babu N, Chandy M, Sundararaj GD. External fixators in haemophilia. Haemophilia. 2004; 10(1):52-7.
• Jayandharan G, Shaji RV, Chandy M, Srivastava A. Identification of factor IX gene defects using a multiplex PCR and CSGE strategy – a first report.  J Thromb Haemost 2003; 1:2051-3
• Shaji RV, Eunice SE, Baidya S, Srivastava A, Chandy M. Determination of the breakpoint and molecular diagnosis of a common alpha-thalassaemia-1 deletion in the Indian population. Br J Haematol. 2003; 123(5):942-7
• Srivastava A, Usher S, Nelson EJ, Jayandharan G, Shaji RV, Chandy M, Seligsohn U, Peretz H. Prenatal diagnosis of Glanzmann thrombasthenia. Natl Med J India. 2003; 16(4):207-8
• Srivastava A. Factor replacement therapy in haemophilia--Are there models for developing countries? Haemophilia. 2003; 9(4):391-6.
• Shaji RV, Edison ES, Poonkuzhali B, Srivastava A, Chandy M. Rapid detection of beta globin gene mutations and polymorphisms by temporal temperature gradient electrophoresis. Clin Chem 2003; 49:777-81
• Shaji RV, Edison ES, Krishnamoorthy R, Chandy M, Srivastava A. Hb Lepore in the Indian population. Hemoglobin. 2003; 27:7-14.
• Srivastava A, Mathews V, Bhurani D, Baidya S, Chandy M. Successful surgical hemostasis in patients with von Willebrand disease following infusion of Koate DVI. Thromb Haemost 2002; 87:541-3
• Shaji RV, Srivastava A, Krishnamoorthy R, Chandy M. Co-existence of a novel beta-globin gene deletion (codons 81-87) with the codon 30 (GàC) mutation in an Indian patient with beta0 thalassemia. Hemoglobin 2002; 26:237-43.
• Mathews V, Balasubramaniam P, Shaji RV, George B, Chandy M, Srivastava A. Arsenic Trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: a single center experience. Am J Hematol 2002;70:292-9
• Kang G, Srivastava A, Pulimood AB, Dennison D, Chandy M. Etiology of diarrhoea in patients undergoing allogeneic bone marrow transplantation in South India. Transplantation 2002; 73:1247-51.
• Subramaniam Shivakumar, Susan Mathew, James Dalton, Mammen Chandy, Alok Srivastava. A complex karyotype involving chromosomes 3,6, 11, 12 and 22 in adult acute lymphoblastic leukemia. Leukemia and Lymphoma 2002;43:1673-7.
• Shivakumar S, Poonkuzhali B, Gunasekaran S, Srivastava A, Chandy M. Cytogenetic, fluorescent in situ hybridization & reverse transcriptase-polymerase chain reaction analysis in acute promyelocytic leukaemia patients. Indian J Med Res 2002;115:59-67
• Shaji RV, Gerard N, Krishnamoorthy R, Srivastava A, Chandy M. A novel beta-thalassemia mutation in an Asian Indian. Hemoglobin 2002;26:49-57.
• Balasubramanian P, Chandy M, Krishnamoorthy R, Srivastava A. Evaluation of existing limited sampling models for busulfan kinetics in children with beta thalassaemia major undergoing bone marrow transplantation. Bone Marrow Transplant. 2001 Nov;28(9):821-5
• Chandy M, Srivastava A, Dennison D, Mathews V, George B. Allogeneic bone marrow transplantation in the developing world: experience from a center in India. Bone Marrow Transplant. 2001 Apr;27(8):785-90.
• Mathews V, Chandy M, Srivastava A. Arsenic trioxide in the management of acute promyelocytic leukaemia. Natl Med J India. 2001;14:215-22. Review.
• Finny GJ, Mathews V, Abraham P, Abraham M, Chandy M, Srivastava A, Nitsche A, Siegert W, Sridharan G. A pilot study on the role of cytomegalovirus & human herpesvirus-6 infections in Indian bone marrow transplant recipients. Indian J Med Res. 2001;114:39-46.
• George B, Mathews V, Srivastava V, Srivastava A, Chandy M. Tuberculosis among allogeneic bone marrow transplant recipients in India. Bone Marrow Transplant. 2001; 27(9):973-5.
• Srivastava A. Choice of factor concentrates for haemophilia: A developing world perspective. Haemophilia 2001;7:117-122
• Balasubramanian P, Srivastava A, Chandy M. Stability of busulfan in frozen plasma and whole blood samples. Clin Chem. 2001;47:766-8
• Poonkhuzhali B, Chandy M, Srivastava A, Dennison D, Krishnamoorthy R. Glutathione S-transferase activity influences busulfan pharmacokinetics in patients with beta thalassemia major undergoing bone marrow transplantation. Drug Metab Dispos. 2001;29:264-7
• Baronciani L; Cozzi G; Canciani MT; Peyvandi F, Srivastava A; Federici AB; Mannucci PM. Molecular characterization of a multiethnic group of 21 patients with type 3 von Willebrand disease. Thromb Haemost 2000;84:536-40
• Mathews V; Srivastava A; Nair SC; Chandy M. Haemostasis with cryoprecipitate in patients undergoing surgery for severe von Willebrand disease. Natl Med J India 2000; 13:188-90
• Sadler JE; Mannucci PM; Berntorp E; Bochkov N; Boulyjenkov V; Ginsburg D; Meyer D; Peake I; Rodeghiero F; Srivastava A. Impact, diagnosis and treatment of von Willebrand disease. Thromb Haemost 2000 Aug;84:160-74
• Shaji RV, Srivastava A, Chandy M, Krishnamoorthy R. A single tube multiplex PCR method to detect the common alpha+ thalassemia alleles.  Blood. 2000 Mar 1;95:1879-80.
• Mathews V, Srivastava A, Nair SC, Chandy M. Haemostasis with cryoprecipitate in patients undergoing surgery for severe von Willebrand disease. Natl Med J India. 2000; 13:188-90
• Lalitha MK, Pai R, Manoharan A, Jesudason MV, Brahmadathan KN, Srivastava A, Chandy M. Systemic bacterial infections in bone marrow transplant patients. Indian J Cancer. 2000;37:10-4.
• Singh S; Cherian RS; George B; Nair S; Srivastava A. Unusual extra-axial central nervous system involvement of non-Hodgkin's lymphoma: magnetic resonance imaging. Australas Radiol 2000;44:112-4
• Mathew LG; Chandy M; Dennison D; Srivastava A; Ganapathy K; Cherian T Successful bone marrow transplantation in an infant with Wiskott-Aldrich syndrome. Indian Pediatr 1999;36:707-10
• George K; George SS; James C; Fernandes HA; Shaji RV; Srivastava A; Chandy M. Transvaginal chorionic villus sampling-an alternative approach.  Aust N Z J Obstet Gynaecol 1999 Nov;39:487-9
• Srivastava A. Factor replacement for haemophilia--should cryoprecipitate be used? Haemophilia 1999;5:301-5
• Poongkuzhali B, Srivastava A, Quernin MH, Dennison D, Aigrain EJ, Kanagasabapathy AS,  Krishnamoorthy R, Chandy M. Pharamacokinetics of oral bususlfan in children with beta thalassaemia major undergoing allogeneic BMT. Bone Marrow Transplant 1999;23:463-7
• Srivastava A, Nair SC, Srivastava VM, Balamurugan AN, Jeyaseelan L, Chandy M, Gunasekaran S. Evaluation of uroprotective efficacy of amifostine against cyclophosphamide induced hemorrhagic cystitis. Bone Marrow Transplant 1999;23:463-467
• Quernin MH, Poongkuzhali B, Medard Y, Dennison D, Srivastava A, Krishnamoorthy R, Chandy M, Aigrain EJ. HPLC method for quantification of busulfan in plasma after derivatization by tetrafluorothiophenol. J Chromatogr B 1999;721:147-152
• Srivastava A, Chandy M, Sunderaj GD, Lee V, Daniel AJ, Dennison D, Nair SC, Matthews V, Anderson G, Nair A, Moses BV, Sudarsanam A. Low dose intermittent factor replacement for post-operative haemostasis in haemophilia. Haemophilia 1998;4:799-801
• Srivastava A.  Delivery of haemaophilia care in the developing world. Haemaophilia 1998;4(Suppl 2):33-40
• Quernin MH, Poonkuzhali B, Montes C, Krishnamoorthy R, Dennison D, Srivastava A, Vilmer E, Chandy M, Aigrain EJ. Quantification of busulfan in plasma by gas chromatogragphy – mass spectrometry following derivatization with tetrafluorothiophenol.  J Chromatography 1998;709:47-56
• Srivastava A, Chuansumrit A, Chandy M, Duraiswamy G, Karabus C. Management of haemophilia in the developing world. Haemophilia 1998;4:474-480
• Bird A, Isarangkura P, Almagro D, Gonzaga A, Srivastava A. Factor concentrates for haemophilia in the developing world. Haemophilia 1998;4:481-485
• Jones S.P, Srivastava A, Dennison D, Mathews M.S. Evaluation of lysis centrifugation method in the detection of fungemia. Ind J Med Microbiol 1997;15:72
• Thomas S, Srivastava A, Jeyaseelan L, Dennison D, Chandy M. NESTROFT as a screening test for the detection of thalassaemia   and common haemoglobinopathies - An evaluation against a high performance liquid chromatographic method. Indian J Med Res 1996; 104: 194-197
• Muralitharan S, Srivastava A, Shaji RV, Mathai M, Srivastava VM, Dennison D, Lu CY, Krishnamoorthy R. Prenatal diagnosis of beta thalassaemia using reverse dot-blot. Natl Med J Ind 1996;9:70-71
• Dabadhghao S, Srivastava A, Dennison D. Bilateral submandibular salivary gland enlargement during chemotherapy for acute myeloid leukaemia. Acta Haem 1996;96:112
• Srivastava VM, Krishnaswami H, Srivastava A, Dennison D, Chandy M. Infections in haematological malignancies - An autopsy study of 72 cases. Trans Royal Soc Trop Med Hyg 1996;90:406-408
• Bhave AA, Srivastava A, Lee V, Daniel AJ, Dennison D, Sunderaj GD, Sudarsanam A. Low dose activated factor IX complex concentrate (FEIBAR) for post-operative haemostasis in a patient with high responding factor VIII inhibitor. Haemophilia 1995,1:274-276
• Poonkuzhuli B, Victoria J, Selvakumar R, Dennison D, Srivastava A, Jeyaseelan L, Chandy M, Kanagasabapathy AS. Comparison of HPLC and EMIT methods of cyclosporine assay in blood after bone marrow transplantation. Indian J Med Res 1995,102:39-41
• Srivastava A, Gottlieb D, Bradstock KF. Diffuse alveolar haemorrhage associated with microangiopathy  after  allogeneic  bone  marrow  transplantation. Bone  Marrow Transplant     1995,15:863-867
• Ramani P, Krishnaswami H, Srivastava A, Dennison D, Chandy M. Infections in bone marrow transplant recepients in south India - a post mortem study. Jr Trop Med Hyg 1994,97:354-356
• Kudva GC, Chandy M, Raghupathy P, Dennison D, Srivastava A, Bhushan V, Singh R. Treatment of childhood acute lymphoblastic leukemia with the BFM regimen. Ind J Cancer 1994,31:78-85
• Kudva GC, Chandy M, Dennison D, Srivastava A, Bhushan V. Treatment of acute lymphoblastic leukemia in adults with modified BFM regimen. Ind J Cancer 1994;31:1-7
• Bhushan V, Chandy M, Khanduri U, Dennison D, Srivastava A, Apte A. Surgery in patients with congenital coagulation disorders. Natl Med J Ind 1994,7:8-12
• Bhushan V, Chandy M, Babu PG, Dennison D, Srivastava A, Saraswati NK, John TJ. Transfusion associated HIV infection in patients with haematological disorders in southern India. Indian J Med Res 1994,99:57-60
• Srivastava A, Pearson H, Coultis N, Jindra J, Bryant J, Wylie B. Removal of HLA class I antigens from platelet surface using acidified chloroquine. Vox Sang 1993,65:146-150
• Srivastava A, Bradstock KF, Szer J, DiBortoli L, Gottlieb D. Busulfan and melphalan as a conditioning regimen for bone marrow transplantation. Bone Marrow Transplant 1993; 12: 323-329
• Exner T, Srivastava A, Favalaro E, Gallo J. An unusual circulating anticoagulant in an elderly patient. Thromb Haemost 1991;65:1364
• Dennison D, Vaughan WP, Srivastava A, Chandy M, Pulimood BM. Bone marrow transplantation in India: appropriate or inappropriate technology? Int J of Third World Studies and Reviews 1990,2:179-184
• Srivastava A, Cherian AM. Recent trends in the chemotherapy of tuberculosis. Ind J Med Sci 1987:17-19
• Srivastava A, Chacko R, John L. Isolated gingival tuberculosis. Ind J Chest Dis All Sci 1986,3:166-168
• Lalitha MK, Anandi V, Srivastava A, Thomas K, Cherian AM, Chandi SM. Isolation of Acanthamoeba Culbertsoni from a patient with meningitis. Jr Clin Microbiol 1985,21:666-667
• Srivastava A, Joseph AG, Cherian AM. Felty's syndrome in an Asian. Br J Rheum 1985,24:303

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